Self-Employed Vs. Else-Employed: Is Overwork Defined Differently Thus Changing Brain Structure Differently?

Is there a new dimension to after-effects of overwork with documented changes in brain structurally?

Can there be an avenue about how overwork changes brain structurally based on the work style after classifying as either self-employed or else-employed?

Could it unravel the differential after-effects if any therein about whether the work style could be confounding overwork definition and thus its after-effects?

Could work-hour-defined overwork have evolved as simplistic quantification for work engagement with its primary utility among else-employed workers?

Could over-reliance on work hours to quantify overwork have been reinforced due to the ongoing rarefaction of self-employed workers secondary to ever-evolving complexities in work systems deterring the safe and sound sustenance of self-employment as the work style?

Does 68-workhour-week mean 100 hours per week for self and kin? Does 52-workhour-week mean 116 hours per week for self and kin? Is such ceiling more applicable to define overwork when workers are else-employed because their work engagement affecting their cognition-emotion could differ from their work-engagement affecting their cognition-emotion if they were to be self-employed wherein engagement for self as well as engagement for work could be in a more likely unison?

If self-employed workers were to work with collegial kin in friends-and-family-owned cooperative work systems, could this amalgamation of work-kin-me potentially aim as near-completeness as possible provided that work-kin-me were to maintain constructive relationships among themselves to collaboratively work for their complementary future by potentially mitigating their cognitively-emotionally perceived overwork if any?